Zopiclone is a common prescription medication prescribed to patients who suffer short term insomnia yet there are concerns regarding the overall effect of this psychiatric medicine on the mental well-being. Although suitable as a sleeping aid, there is a rising amount of evidence that can zopiclone cause depression or exacerbate the condition of depression and this occurs particularly when used over a prolonged period or in people at risk. This paper reviews the issue of whether zopiclone can cause depression, the impact of using this medication on mood, and what an individual must learn prior to using or continuing to use zopiclone.
How Zopiclone Works
Zopiclone, a low-affinity benzodiazepine sedative-hypnotic that primarily use in the treatment of insomnia in the short term. It acts by increasing the activity of GABA neurotransmitter in the brain that produces calming and sleep induction. Nevertheless, these neurochemical changes have an impact on emotional stability and mental functions as well.
Depression as a Reported Side Effect.
The adverse effects of zopiclone documented include depressive symptoms like low mood, sadness and emotional flatness. The clinical evidence and patient experiences indicate that the emotional reactions to this medication may be depression or even depressed mood, which exacerbates the existing mental health issues or leads to the emergence of new ones.
Mechanisms between Zopiclone and Depression.
A number of mechanisms uses to explain the relationship between zopiclone and depression:
Neurochemical imbalance: The long-term or excessive use of zopiclone can change the normal GABA activity and it increases the risk of an individual being in a depressive and anxious mood, particularly when he or she is quitting or has been reduced.
Withdrawal effects: A sudden cessation, particularly following high-dose or prolonged intake may also cause various emotional consequences, including depression, irritability, and even psychosis in the worst-case scenario.
The risks of comedication: In individuals using other psychiatric medicines or in individuals with a mental health diagnosis, the likelihood of depressive symptoms increases with the administration of zopiclone.
Scientific Evidence and Clinical Evidence.
The psychiatric risk of zopiclone approved by medical instructions and reports. Regulators have reported effects of depression, suicidal and psychotic effects of its use. According to case reports, dependency and withdrawal can both lead to serious neuropsychiatric symptoms, such as major depression and emotional instability. Other people report that they become emotionally numb or get zopiclone rage or major depressions following consistent use.
Who Is Most at Risk?
The people who are at a higher risk of developing depression due to zopiclone include:
Patients who have history of depression, anxiety, or other mental health disorder.
Individuals who take zopiclone over the course of weeks or months, or at an overdose level.
Patients who abruptly withdraw zopiclone when used regularly, and experience withdrawal.
Minimising the Risks
In order to minimize the possibility of depression when using zopiclone:
The health practitioner recommends.
Conduct regular check-ups on mental and emotional health either when mood changes noticeable.
Any depressive history should be discussed with a physician before taking zopiclone.
Seek medical care when new or worsening symptoms should occur such as sadness, hopelessness, or emotional instability.
Conclusion
Even though zopiclone may be used in short-term insomnia. It is established that it may induce or enhance depression in vulnerable populations especially when abused, addicted or withdrawn. The close attention and medical control are necessary to reduce psychiatric and emotional risks. Reporting a change in mood to a healthcare team member at all times is necessary to implement sleep issues in a safe and appropriate manner.
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