There are medicines, vitamins, and other substances that should not be administered together with zopiclone. Because they can interact and cause harmful effects or diminished polarity.
The awareness of these combinations will contribute to avoidance of severe complications and provide safety of zopiclone in the treatment of sleep disorders. So in this blog you will find out what can you not take with zopiclone
Central Nervous System (CNS)
DepressantsZopiclone is a sedative-hypnotic which when used together with other medicine that depress the central nervous system. It may increase the effects of Zopiclone like drowsiness, confusion, poor motor control and even ruin respiration.
This group contains:Other tranquilizers or sleeping pills (e.g., benzodiazepines such as diazepam or temazepam)
Opioid painkillers (e.g., codeine, morphine, tramadol, oxycodone, methadone, pethidine): The combination significantly increases the risk of harmful sedation, breathing problems, coma, and even death.
Antihistamines of the sedative type (e.g., chlorphenamine, promethazine):
It may also cause an increase in daytime somnambulism and daytime functioning is complicated.
Antipsychotics or antidepressants: When used with SSRIs, SNRIs, or other mood-altering medications, antipsychotics.
And antidepressants interact to amplify the effects of the former and heighten the chances of confusion or lack of coordination.
Anticonvulsants: Can potentially enhance drowsiness and the effect of zopiclone may be compromised by others (such as carbamazepine, phenobarbital, phenytoin), which may interfere with its metabolism.
CYP 3A4 Inhibitors and Inducers.
Metabolism of Zopiclone uses the liver CYP3A4 enzyme. There are a number of medicines that may alter the breakdown of the zopiclone, causing either increased effects or decreased efficacy:
CYP3A4 inhibitors:
These enhance the activity of zopiclone and its side effects. Examples are:Some antibiotics (erythromycin, clarithromycin)
Antifungals (itraconazole, ketoconazole)
.HIV medicines (ritonavir).
Enhanced activity of cyanoethanol hydrochloride (CYP3A4): These reduce the action of zopiclone:Antibiotics such as rifampicin.
Anti-epileptic (carbamazepine, phenobarbital, phenytoin).
St John herbal supplement (St John Wort)
Herbal Supplements, Vitamins, and Supplements.
Although most supplements might appear to be harmless. Some of the herbal forms of remedies, particularly those with a sedative effect must be avoided St Johns Wort reduces the effect of zopiclone through enzyme induction.
Some other sedative herbs or sleep aids (e.g., valerian) may result in excessive drowsiness when combined with zopiclone.
Vitamins and supplements: It is always important to inform the healthcare provider about all supplements, and an unexpected interaction may arise.
Alcohol: Zopiclone should not use together with alcohol.
The two substances inhibit the CNS and both cause a significant increase in the risk of accidents, excessive sedation, memory loss, and poor judgment:
Effects include: Severe drowsiness, confusion, lack of motor coordination, breathing difficulties, coma or death.
Precautions for Safe Use
Always tell the doctor or pharmacist about all medicines, herbal preparations, or supplements that are taken.
Conclusion
Interactions Zopiclone should not be combined with other CNS depressants, medicines that are CYP3A4-inhibitors, sedative herbs, or alcohol, as it can lead to dangerous and even fatal resuls. Never introduce any new medication or supplement without medical advice to the recommendations of safe and effective treatment of insomnia. To buy Zopiclone online, visit our website.